“Apply directly to the forehead,” infamously commanded a TV commercial for HeadOn, a pain reliever introduced in 2006 by a company called Miralus Healthcare. The product, which costs $25 and is sold in drug stores and online, claims to relieve headache and migraine pain. It is not a pill nor a solution but instead a waxy paste. Topical medicines are sometimes used to relieve local skin and muscle pains, but the idea that it could somehow relieve headache pain has aroused plenty of skepticism. According to its Amazon.com listing, “Head On Pain Reliever apply directly to the forehead. It is invisible and non greasy. Homeopathic. It’s [sic] can be used as often as needed. Safe to use with other medications.”

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